Recombinant Human Lipopolysaccharide-binding protein/LBP Protein

Artikelnummer: ABB-RP00418
Artikelname: Recombinant Human Lipopolysaccharide-binding protein/LBP Protein
Artikelnummer: ABB-RP00418
Hersteller Artikelnummer: RP00418
Alternativnummer: ABB-RP00418-10UG, ABB-RP00418-50UG
Hersteller: ABclonal
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Immunogen: Ala26-Val481
Alternative Synonym: BPIFD2,LBP
This protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Konzentration: < 1 EU/µg of the protein by LAL method.
Molekulargewicht: 51.95 kDa
NCBI: 3929
UniProt: P18428
Reinheit: 95 % as determined by SDS-PAGE.
Formulierung: Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.Contact us for customized product form or formulation.
Target-Kategorie: Lipopolysaccharide-binding
Application Verdünnung: Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.Contact us for customized product form or formulation.
Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human Lipopolysaccharide-binding protein/LBP Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.