Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloidprecursor, NACP, Snca
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinsons Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB).
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Target-Kategorie:
SNCA/Alpha-Synuclein
Application Verdünnung:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Cytokines & Cytokine Receptors
Recombinant Mouse Alpha-Synuclein/SNCA Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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