Recombinant Mouse Fc-gamma RIII/CD16 Protein, Human
Artikelnummer:
ABB-RP00761
Hersteller Artikelnummer:
RP00761
Alternativnummer:
ABB-RP00761-10UG, ABB-RP00761-50UG
Hersteller:
ABclonal
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Immunogen:
Ala31-Thr215
Alternative Synonym:
Low affinity immunoglobulin gamma Fc region receptor III, Fcgr3, Fc gamma Receptor III, CD-antigen 16, CD16, FcRIII, IgG Fc receptor III
Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Igsuperfamily. Based on close relationships in their extracellular domains, the Fc gamma Rs have been dividedinto three classes composing of Fc gamma RI (CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Eachgroup may be encoded by multiple genes and exist in different isoforms depending on species and cell type.Mouse CD16 is a type I transmembrane protein having two extracellular Ig-like domains consisting ofimmunoglobulin domain, repeat, signa and transmembrane, transmembrane helix. It is expressed on a varietyof myeloid and lymphoid cells and associates with Fc R gamma to deliver an activating signal upon ligandbinding. Fcgr3 is IgG binding and activation or inhibition of immune responses such as antibody-dependentcellular cytotoxicity, phagocytosis, cell surface receptor signaling pathway and positive regulation of typeI/IIa/III hypersensitivity.
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Target-Kategorie:
Fc-gamma RIII/CD16
Application Verdünnung:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Fc & Fc Receptor
Recombinant Mouse Fc-gamma RIII/CD16 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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