Recombinant Human Estrogen receptor/ESR1 Protein, E. coli
Artikelnummer:
ABB-RP00815
Hersteller Artikelnummer:
RP00815
Alternativnummer:
ABB-RP00815-50UG, ABB-RP00815-10UG
Hersteller:
ABclonal
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Immunogen:
Met1-Gln116
Alternative Synonym:
ER, ESR, ESRA, ESTRR, Era, NR3A1,ESR1,ESRalpha,ESR,ESRA,ESTRR,Era,NR3A1,ER alpha
Estrogen Receptor is a major ligand---activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5 UTRs and use different promoters.
Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.2Contact us for customized product form or formulation.
Target-Kategorie:
Estrogen receptor/ESR1
Application Verdünnung:
Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.2Contact us for customized product form or formulation.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human Estrogen receptor/ESR1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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