Recombinant Mouse IL-4 Protein, Human

Produktübersicht

• Artikelname: Recombinant Mouse IL-4 Protein, Human
• Artikelnummer: ABB-RP01161
• Hersteller Artikelnummer: RP01161
• Alternativnummer: ABB-RP01161-100UG, ABB-RP01161-10UG, ABB-RP01161-50UG, ABB-RP01161-20UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: His23-Ser140
• Alternative Synonym: Il-4, BSF-1,IL4

Produktbeschreibung

Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It enhances both secretion and cell surface expression of IgE and IgG1. Interleukin-4 / IL4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Interleukin-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype.

Produkteigenschaften

• Konzentration: < 0.1 EU/µg of the protein by LAL method.
• Molekulargewicht: 14.15 kDa
• NCBI: 16189
• UniProt: P07750
• Reinheit: 95 % as determined by SDS-PAGE, 95 % as determined by HPLC.
• Formulierung: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
• Target-Kategorie: IL-4

Anwendungsbeschreibung

• Application Verdünnung: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Interleukin,Cell Culture related

Bilder

Recombinant Mouse IL-4 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Recombinant Mouse IL-4 Protein is greater than 95% as determined by SEC-HPLC.

Recombinant Mouse IL-4 promote the proliferation of MC/9 2 mouse mast cells. The ED<,sub>,50<,/sub>, for this effect is 2.8-11.3 pg/mL, corresponding to a specific activity of 8.85*10<,sup>,7<,/sup>,~3.57*10<,sup>,8<,/sup>, units/mg.

Recombinant Mouse IL4 stimulates cell proliferation of HT-2 mouse T cells. The ED<,sub>,50<,/sub>, for this effect is 1.18-4.70 ng/mL, corresponding to a specific activity of 2.13*10<,sup>,5<,/sup>,~8.51*10<,sup>,6<,/sup>, units/mg.