Recombinant Mouse Galectin-9/LGALS9 Protein, E. coli

Produktübersicht

• Artikelname: Recombinant Mouse Galectin-9/LGALS9 Protein, E. coli
• Artikelnummer: ABB-RP02002LQ
• Hersteller Artikelnummer: RP02002LQ
• Alternativnummer: ABB-RP02002LQ-50UG,ABB-RP02002LQ-10UG
• Hersteller: ABclonal
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: Met1-Thr322
• Alternative Synonym: Galectin-9, Lgals9, Gal-9

Produktbeschreibung

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkins disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin alpha4beta1.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 62.8 kDa
• Tag: N-GST
• NCBI: 16859
• UniProt: O08573
• Quelle: E. coli
• Reinheit: 90 % as determined by SDS-PAGE.
• Formulierung: Supplied as a 0.2 µm filtered solution of 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5Contact us for customized product form or formulation.
• Target-Kategorie: Galectin-9/LGALS9

Anwendungsbeschreibung

• Application Verdünnung: Supplied as a 0.2 µm filtered solution of 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5Contact us for customized product form or formulation.
• Anwendungsbeschreibung: ResearchArea: Immune Checkpoint