Recombinant Human SUMO-1 Protein, E. coli

Produktübersicht

• Artikelname: Recombinant Human SUMO-1 Protein, E. coli
• Artikelnummer: ABB-RP02176
• Hersteller Artikelnummer: RP02176
• Alternativnummer: ABB-RP02176-50UG
• Hersteller: ABclonal
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Immunogen: Met1-Val101
• Alternative Synonym: DAP1,GMP1,OFC10,PIC1,SENP2,SMT3,SMT3C,SMT3H3,UBL1,SUMO1,SUMO-1, DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1, small ubiquitin-like modifier 1

Produktbeschreibung

Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 13.7 kDa
• NCBI: 7341
• UniProt: P63165
• Reinheit: 95 % as determined by SDS-PAGE.
• Formulierung: Lyophilized from a 0.2 µm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .Contact us for customized product form or formulation.
• Target-Kategorie: SUMO-1

Anwendungsbeschreibung

• Application Verdünnung: Lyophilized from a 0.2 µm filtered solution of 50mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.5 .Contact us for customized product form or formulation.
• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein

Bilder

Recombinant Human SUMO-1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.