Recombinant Mouse TNFRSF18/GITR/CD357 Protein, Human
Artikelnummer:
ABB-RP02184
Hersteller Artikelnummer:
RP02184
Alternativnummer:
ABB-RP02184-10UG, ABB-RP02184-50UG
Hersteller:
ABclonal
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Immunogen:
Ser22-His153
Alternative Synonym:
AITR, Gitr, Tnfrsf18
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA , isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Target-Kategorie:
TNFRSF18/CD357
Application Verdünnung:
Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Immune Checkpoint,TNF family
Recombinant Mouse TNFRSF18/GITR/CD357 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
