Biotinylated Recombinant Human Siglec-10 (R119A) Protein
Artikelnummer:
ABB-RP02585B
Hersteller Artikelnummer:
RP02585B
Alternativnummer:
ABB-RP02585B-100UG
Hersteller:
ABclonal
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Immunogen:
Met17-Thr546
Alternative Synonym:
SLG2, SIGLEC10, MGC126774, PRO940
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Formulierung:
Lyophilized from a 0.22 µm filtered solution of 20 mM Tirs 150 mM NaCl, 200 mM L-arginine, pH 8.0.
Target-Kategorie:
Siglec-10 (R119A)
Application Verdünnung:
Lyophilized from a 0.22 µm filtered solution of 20 mM Tirs 150 mM NaCl, 200 mM L-arginine, pH 8.0.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein
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