Biotinylated Recombinant Human TNFSF18/GITR Ligand Trimer Protein (Primary Amine Labeling)

Produktübersicht

• Artikelname: Biotinylated Recombinant Human TNFSF18/GITR Ligand Trimer Protein (Primary Amine Labeling)
• Artikelnummer: ABB-RP02600B
• Hersteller Artikelnummer: RP02600B
• Alternativnummer: ABB-RP02600B-100UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Immunogen: Gln50-Ser177
• Alternative Synonym: TNFSF18, AITRL, TL6, GITRL, GITR Ligand

Produktbeschreibung

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept .

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 47.5 kDa
• NCBI: 8995
• UniProt: Q9UNG2
• Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Formulierung: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
• Target-Kategorie: TNFSF18/GITR Ligand

Anwendungsbeschreibung

• Application Verdünnung: Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein