Recombinant Human/Mouse Histone H3.1 Protein, E. coli
Artikelnummer:
ABB-RP03190
Hersteller Artikelnummer:
RP03190
Alternativnummer:
ABB-RP03190-1000UG
Hersteller:
ABclonal
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human, Mouse
Immunogen:
Met1-Ala136
Alternative Synonym:
histone cluster 1, H3a, Histone H3.1
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expressed during the S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher-order chromatin structures.
Lyophilized from sterile 2 mM beta-Mercaptoethanol. Please contact us for any concerns or special requirements. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Target-Kategorie:
HIST1H3A
Application Verdünnung:
Lyophilized from sterile 2 mM beta-Mercaptoethanol. Please contact us for any concerns or special requirements. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Anwendungsbeschreibung:
Cross-Reactivity: Please contact us for reconstitution instructions. ResearchArea: Other Recombinant Protein
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