Recombinant Human Asparaginyl endopeptidase/Legumain/LGMN Protein

Produktübersicht

• Artikelname: Recombinant Human Asparaginyl endopeptidase/Legumain/LGMN Protein
• Artikelnummer: ABB-RP03221LQ
• Hersteller Artikelnummer: RP03221LQ
• Alternativnummer: ABB-RP03221LQ-50UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Immunogen: Ile18-Tyr433
• Alternative Synonym: Legumain, Asparaginyl Endopeptidase, Protease Cysteine 1, LGMN, PRSC1

Produktbeschreibung

Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family. Though it is found in many tissues, it is highly expressed in the kidney, heart, and placenta. Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly, especially under acidic conditions. Over-expression Legumain in tumors is significant for invasion and metastasis. In addition, Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 48.72 kDa
• Tag: C-His
• NCBI: 5641
• UniProt: AAH03061.1
• Quelle: Mammalian expression system
• Reinheit: 95 % as determined by SDS-PAGE.
• Formulierung: Supplied as a 0.2 µm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.
• Target-Kategorie: LGMN

Anwendungsbeschreibung

• Application Verdünnung: Supplied as a 0.2 µm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 10% Glycerol, pH 8.0.
• Anwendungsbeschreibung: ResearchArea: Other Recombinant Protein