Recombinant Human Ubiquitin (I44A) protein, E. coli
Artikelnummer:
ABB-RP10066LQ
Hersteller Artikelnummer:
RP10066LQ
Alternativnummer:
ABB-RP10066LQ-25UG, ABB-RP10066LQ-50UG
Hersteller:
ABclonal
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be conjugated on proteins as monoUb or polyUb chains. Protein ubiquitination plays both proteolytic and nonproteolytic functions. Usually, polyubiquitinated proteins are targeted to the 26S proteasome for proteolysis. Typical concentration to support in vitro ubiquitination is 50-100 µM. I44 is one of the key residues of the hydrophobic patch on Ub surface. The I44A mutant inhibits the interactions of Ub with many Ub-binding domains.
Konzentration:
Please contact us for more information.
Reinheit:
95% as determined by reducing SDS-PAGE.
Formulierung:
20 mM Tris, 150 mM NaCl, 2 mM betaME, 10% Glycerol
Target-Kategorie:
Ubiquitin (I44A)
Application Verdünnung:
20 mM Tris, 150 mM NaCl, 2 mM betaME, 10% Glycerol
Anwendungsbeschreibung:
ResearchArea: Ubiquitination related reagent
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