Human CD52 Monoclonal Antibody

Artikelnummer: ABB-YR0012
Artikelname: Human CD52 Monoclonal Antibody
Artikelnummer: ABB-YR0012
Hersteller Artikelnummer: YR0012
Alternativnummer: ABB-YR0012-1MG,ABB-YR0012-5MG,ABB-YR0012-20MG
Hersteller: ABclonal
Kategorie: Antikörper
Applikation: ELISA, NeA
Immunogen: Human CD52
Alternative Synonym: HE5, CDW52, EDDM5
Alemtuzumab Biosimilar uses the same protein sequences as the therapeutic antibody alemtuzumab.Alemtuzumab is a medication used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. In CLL, it has been used as both a first line and second line treatment. In MS it is generally only recommended if other treatments have not worked. It is given by injection into a vein.It is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction.
NCBI: 1043
UniProt: P31358
Reinheit: >95% Determined by SDS-PAGE
Target-Kategorie: CD52
Application Verdünnung: In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Anwendungsbeschreibung: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay. ResearchArea: Cancer immunology