Human CD20 Monoclonal Antibody, Endotoxin 0.05 EU/mg

Artikelnummer: ABB-YR0131
Artikelname: Human CD20 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Artikelnummer: ABB-YR0131
Hersteller Artikelnummer: YR0131
Alternativnummer: ABB-YR0131-5MG,ABB-YR0131-20MG
Hersteller: ABclonal
Kategorie: Antikörper
Applikation: ELISA, NeA
Immunogen: Human CD20
Alternative Synonym: B1, S7, Bp35, CD20, FMC7, CVID5, LEU-16, MS4A1
Obinutuzumab is an antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil.In contrast to rituximab, which is a classic type I CD20 antibody, obinutuzumab binds to type II CD20 antibodies. This allows obinutuzumab to have a much higher induction of antibody-dependant cytotoxicity and a higher direct cytotoxic effect than the classic CD20 antibodies.
NCBI: 931
UniProt: P11836
Reinheit: >95% Determined by SDS-PAGE
Target-Kategorie: CD20
Application Verdünnung: In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Anwendungsbeschreibung: Cross-Reactivity: <0.05EU/mg (<0.00005EU/µg) Determined by LAL gel clotting assay. ResearchArea: Cancer immunology