In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)

Produktübersicht

• Artikelname: In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)
• Artikelnummer: ABB-YR0292
• Hersteller Artikelnummer: YR0292
• Alternativnummer: ABB-YR0292-25MG,ABB-YR0292-5MG,ABB-YR0292-1MG
• Hersteller: ABclonal
• Kategorie: Antikörper
• Applikation: FC, IHC
• Immunogen: mouse PD-1-transfected BHK cells

Produktbeschreibung

The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.

Produkteigenschaften

• Reinheit: >95% Determined by SDS-PAGE

Anwendungsbeschreibung

• Application Verdünnung: In Vivo Grade Recombinant Rat IgG2a Kappa Isotype Control Antibody
• Anwendungsbeschreibung: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay