PEG (Polyethylene glycol) is a polyether compound with many applications from industrial manufacturing to medicine. PEGylation is a technology that covalently couples non-toxic, hydrophilic polyethylene glycol (PEG) to the drug. It is an FDA-approved method for the delivery of protein drugs. PEG modification can reduce the drug immunogenicity and antigenicity. PEGylated drug decelerates renal excretion, improves stability towards proteolysis and increases its half-life in blood. Accurate and sensitive quantification of PEG conjugates is important for PEG conjugated product development and pharmaceutical study. Polyethylene glycol (PEG) antibody is a useful tool for the detection of PEGylated molecules.
Isotyp:
IgG1
Reinheit:
>95% Determined by SDS-PAGE
Anwendungsbeschreibung:
Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay. ResearchArea: Cancer immunology
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