NALE(TM) Recombinant Human PD-1 rabbit monoclonal Antibody (Clone: ABMRR01) (No Azide Low Endotoxin), Clone: [ABMRR01], Other, Monoclonal
Artikelnummer:
ABI-10-2001-NALE
Hersteller Artikelnummer:
10-2001-NALE
Alternativnummer:
ABI-10-2001-NALE-100UG
Hersteller:
Abeomics
Wirt:
Other
Kategorie:
Antikörper
Applikation:
FA, FACS, WB
Spezies Reaktivität:
Human
Alternative Synonym:
PDCD1, PD1, CD279
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
