Monoclonal Antibody to TLR7 (Clone: ABM2C27), Clone: [ABM2C27], Mouse
Artikelnummer:
ABI-10-3015-25
Hersteller Artikelnummer:
10-3015-25
Alternativnummer:
ABI-10-3015-25-25UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IHC
Spezies Reaktivität:
Human
Immunogen:
A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody.
Alternative Synonym:
TLR7||UNQ248/PRO285
TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells.
