Monoclonal antibody to Mouse TLR4 CD284 (Clone: MTS510) FITC Conjugated, Clone: [MTS510], Rat
Artikelnummer:
ABI-10-3022-F-25
Hersteller Artikelnummer:
10-3022-F-25
Alternativnummer:
ABI-10-3022-F-25-25UG
Hersteller:
Abeomics
Wirt:
Rat
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Mouse
Immunogen:
This antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2
Konjugation:
FITC
Alternative Synonym:
CD284
TLR4 (Toll-like receptor-4) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. It primarily mediates cellular signaling induced by Gram negative bacteria. TLR4 is highly specific for LPS and it is associated with CD14, a co-receptor for LPS. The downstream signaling pathway of TLR4 leads to the activation of NF-kappaB through myeloid differentiation protein (MyD88) and IL-1 receptor-associated kinase in various cell types.
