Monoclonal Antibody to Mouse EBI3 (Clone: ABM2C40), Clone: [ABM2C40], Rat
Artikelnummer:
ABI-10-4021
Hersteller Artikelnummer:
10-4021
Alternativnummer:
ABI-10-4021-100UG
Hersteller:
Abeomics
Wirt:
Rat
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Mouse
Immunogen:
A full length recombinant mEBI3 protein was used as the immunogen for this antibody.
Alternative Synonym:
Ebi3||Il27b
Epstein-Barr Virus Induced Gene 3 (EBI3) is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. EBI3, as part of the immunosuppressive IL-35 cytokine, plays an important role in the regulation of intestinal immune responses by controlling overwhelming T-cell activation. EBI3 deficiency does not lead to changes in intestinal pathology in trinitrobenzene sulfonic acid colitis, but is protective in oxazolone-induced colitis.