Human PBMCs were used as immunogen for the CD3 antibody.
Konjugation:
APC
Alternative Synonym:
CD3D||T3D
CD3D is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).
Fig-1: Cell surface flow analysis of hCD3 in PBMC using 0.5 µg/10 6 cells. Green represents isotype control (ABEOMICS), red represents APC conjugated anti-hCD3 antibody (10-4089AC).
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