Monoclonal Antibody to Mouse CD3 (Clone: 145-2C11), Clone: [145-2C11], Hamster
Artikelnummer:
ABI-10-4123
Hersteller Artikelnummer:
10-4123
Alternativnummer:
ABI-10-4123-100UG
Hersteller:
Abeomics
Wirt:
Hamster
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Mouse
Immunogen:
Mouse BM10-37 cytotoxic T lymphocytes were used as immunogen for this antibody.
Alternative Synonym:
T-cell surface glycoprotein CD3 zeta chain||T-cell receptor T3 zeta chain||CD247
CD3 is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).