Monoclonal Antibody to CK19 (Clone: A53-B/A2), Clone: [A53-B/A2], Mouse
Artikelnummer:
ABI-10-7506
Hersteller Artikelnummer:
10-7506
Alternativnummer:
ABI-10-7506-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Human breast cancer MCF-7 cells were used as the immunogen for the Keratin-19 antibody.
Alternative Synonym:
KRT19
Keratin-19 (K19) is a type I intermediate filament protein and one of the best characterized of the keratins expressed in mature striated muscle. Keratin-19 is expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium. Keratin-19 has been used as a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer. Immunohistochemical data has shown that Keratin-19 may be uses as a marker for human skin stem cells.