Rabbit Monoclonal Antibody to EpCAM (Clone: ABM53D8), Clone: [ABM53D8]

Produktübersicht

• Artikelname: Rabbit Monoclonal Antibody to EpCAM (Clone: ABM53D8), Clone: [ABM53D8]
• Artikelnummer: ABI-10-7611
• Hersteller Artikelnummer: 10-7611
• Alternativnummer: ABI-10-7611-100UG
• Hersteller: Abeomics
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: A partial length recombinant EpCam protein (amino acid 56-267) was used as immunogen for this antibody.
• Alternative Synonym: EPCAM||GA733-2||M1S2||M4S1||MIC18||TACSTD1||TROP1

Produktbeschreibung

EpCAM (epithelial specific antigen) is an ~40 kDa transmembrane glycoprotein involved in a number of cellular processes including adhesion, proliferation, maintenance of stemness, migration and invasion. EpCAM is expressed on most, but not all, normal epithelia and their corresponding malignancies. Although the role of EpCAM expression in tumorigenesis remains to be fully elucidated, EpCAM may downregulate immunity and help tumors actively escape from immune surveillance.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ABM53D8]
• NCBI: 4072
• UniProt: P16422
• Reinheit: Protein G Chromatography
• Formulierung: Purified
• Target-Kategorie: EpCAM
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot analysis: 2-4 µg/ml

Bilder

Fig-1: Western blot analysis of EpCAM. Anti- EpCAM antibody (Clone: ABM53D8) was used at 2 µg/ml on Raji, HCT116, Molt-4 and Ramos lysates.