Mouse Monoclonal Antibody To N-Cadherin (Clone: 8C11), Clone: [8C11]
Artikelnummer:
ABI-10-7653
Hersteller Artikelnummer:
10-7653
Alternativnummer:
ABI-10-7653-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FACS, IHC, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
Recombinant human N-cadherin extracellular domain (exact sequence is proprietary)
N-cadherin(CD325) is a 140 kD protein belongs to a transmembrane molecules that mediate calcium dependent intracellular adhesion. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.
Flow Cytometry: 0.5-1 µg/10 6 cells, Immunofluorescence :1-2 µg/ml, Western Blotting: 0.5-1.0 µg/ml, Immunohistology (Formalin-fixed) : 0.5-1.0 µg/ml, for 30 minutes at RT. (Optimal dilution for a specific application should be determined.)
Fig. 1: Cell Surface FLOW analysis of N-Cadherin in KG1 cells using 0.5 µg of antibody (Clone: 8C11). Green represents isotype control, red represents anti-N Catherine (10-7653) antibody. Goat anti-mouse PE conjugate was used as secondary antibody.
Fig. 2: Cell Surface FLOW analysis of N-Cadherin in human PBMC Monocytes gated) using 0.5 µg of antibody (Clone: 8C11). Green represents isotype control, red represents anti-N Catherine (cat no. 10-7653) antibody. Goat anti-mouse PE conjugate was used as secondary antibody.
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