A partial length recombinant HOXB4 protein (amino acids1-221) was used as the immunogen for this antibody.
Alternative Synonym:
HOXB4||HOX2F
HoxB4 is a member of the highly conserved homeodomain TF (Transcription Factor) family. It was the first transcription factor shown to lead to profound HSC (hematopoietic stem cells) expansion in vitro and in vivo when expressed ectopically in adult BM cells and ESCs (Embryonic Stem Cells). HoxB4 is used to promote hematopoietic differentiation from human embryonic stem cells or from human induced pluripotent stem cells.