N-terminal of SARS-CoV-2/COVID-19 Nucleocapsid protein was used as the immunogen for this antibody.
The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.
Klonalität:
Polyclonal
Reinheit:
Protein A Chromatography
Formulierung:
Purified
Target-Kategorie:
SARS-CoV2 N-Term Nucleocapsid
Application Verdünnung:
Recommended dilutions: WB: 0.1-0.5 µg/ml. However, this need to be optimized based on the research applications.
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