A partial length recombinant Gbp1 protein (amino acids 200-592) was used as the immunogen for this antibody.
Alternative Synonym:
GBP1
Interferon-induced guanylate-binding protein 1 in humans is encoded by the GBP1 gene belongs to the dynamin superfamily of large GTPases and induced by interferons. GBP1 hydrolyzes GTP to GMP in two consecutive cleavage reactions and also exhibits antiviral activity against influenza virus. Diseases associated with GBP1 include pseudo pseudo hypoparathyroidism and aneurysmal bone cysts. It is widely expressed on central nervous system, mammary gland, skeletal muscle, skin, small intestine, stomach, etc.
