Full length recombinant Hes7 protein was used as the immunogen for this antibody.
Alternative Synonym:
HES7||BHLHB37
HES7 (Hes family bHLH transcription factor 7) is a member of the Hairy-and-enhancer-of-split (HES) family of transcription factors, which play a role in somite formation. This is expressed in an oscillatory manner during the process of somitogenesis, a process by which somites (bilaterally paired blocks of mesoderm) form and give rise to skeletal muscle, cartilage, tendons, endothelial cells, and dermis. Missense mutations of HES7 have been reported to cause SCDO4 (Spondylocostal Dysostosis 4), an inherited disorder that is characterized by the presence of extensive hemivertebrae, truncal shortening and abnormally aligned ribs.
