Recombinant Rabbit Monoclonal Antibody to MART-1 / Melan-A / MLANA (Melanoma Marker)(Clone : MLANA/1409R), Clone: [MLANA/1409R]

Produktübersicht

• Artikelname: Recombinant Rabbit Monoclonal Antibody to MART-1 / Melan-A / MLANA (Melanoma Marker)(Clone : MLANA/1409R), Clone: [MLANA/1409R]
• Artikelnummer: ABI-12-1021-20
• Hersteller Artikelnummer: 12-1021-20
• Alternativnummer: ABI-12-1021-20-20UG
• Hersteller: Abeomics
• Kategorie: Sonstiges
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Recombinant human full-length MLANA protein
• Alternative Synonym: Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA

Produktbeschreibung

This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MLANA/1409R]
• NCBI: 2315
• UniProt: Q16655
• Reinheit: Purified Ab with BSA and Azide at 200ug/ml
• Formulierung: Purified
• Target-Kategorie: MART-1 / Melan-A / MLANA (Melanoma Marker)
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western Blot (2-4µg/ml), Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for