Recombinant Rabbit Monoclonal Antibody to Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(Clone : TYRP1/1564R), Clone: [TYRP1/1564R]

Produktübersicht

• Artikelname: Recombinant Rabbit Monoclonal Antibody to Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(Clone : TYRP1/1564R), Clone: [TYRP1/1564R]
• Artikelnummer: ABI-12-1044
• Hersteller Artikelnummer: 12-1044
• Alternativnummer: ABI-12-1044-100UG
• Hersteller: Abeomics
• Kategorie: Sonstiges
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse
• Immunogen: Recombinant human full-length TYRP1 protein
• Alternative Synonym: 5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP

Produktbeschreibung

It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [TYRP1/1564R]
• NCBI: 7306
• UniProt: P17643
• Reinheit: Purified Ab with BSA and Azide at 200ug/ml
• Formulierung: Purified
• Target-Kategorie: Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),