Anti-Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rEGP40/1372), Clone: [rEGP40/1372]

Produktübersicht

• Artikelname: Anti-Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rEGP40/1372), Clone: [rEGP40/1372]
• Artikelnummer: ABI-12-1176-20
• Hersteller Artikelnummer: 12-1176-20
• Alternativnummer: ABI-12-1176-20-20UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Sonstiges
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant ECD-fragment of human EpCAM protein (around aa 77-202) (exact sequence is proprietary)
• Alternative Synonym: Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TROP1, Tumor-associated Calcium Signal Transducer 1 (TACSTD1), ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, Flotillin-2, Memb

Produktbeschreibung

EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rEGP40/1372]
• NCBI: 4072
• UniProt: P16422
• Reinheit: Protein A/G
• Formulierung: Purified
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western Blot (1-2µg/ml), ,Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT f