Anti-MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Recombinant Mouse Monoclonal Antibody (Clone:rMUC18/1130), Clone: [rMUC18/1130]

Produktübersicht

• Artikelname: Anti-MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Recombinant Mouse Monoclonal Antibody (Clone:rMUC18/1130), Clone: [rMUC18/1130]
• Artikelnummer: ABI-12-1217-20
• Hersteller Artikelnummer: 12-1217-20
• Alternativnummer: ABI-12-1217-20-20UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Sonstiges
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human MUC18 protein
• Alternative Synonym: Cell Surface Glycoprotein MUC18, Cell Surface Glycoprotein P1H12, Gicerin, Melanoma Adhesion Molecule (MCAM), Melanoma Associated Glycoprotein MUC18, Melanoma Cell Adhesion Molecule, Melanoma-associated Antigen A32, Mel-CAM, S-endo 1 Endothelial-associated Antigen, Sendo1

Produktbeschreibung

Mel-CAM belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rMUC18/1130]
• NCBI: 4162
• UniProt: P43121
• Reinheit: Protein A/G
• Formulierung: Purified
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 8.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)