Anti-PD-1(Opdivo)(Nivolumab biosimilar) mAb, IgG4, Human Humanized, Monoclonal

Produktübersicht

• Artikelname: Anti-PD-1(Opdivo)(Nivolumab biosimilar) mAb, IgG4, Human Humanized, Monoclonal
• Artikelnummer: ABI-12-2001
• Hersteller Artikelnummer: 12-2001
• Alternativnummer: ABI-12-2001-100UG
• Hersteller: Abeomics
• Wirt: Human Humanized
• Kategorie: Antikörper
• Applikation: ELISA
• Spezies Reaktivität: Human

Produktbeschreibung

Nivolumab (Optivo), Pembrolizumab are both PD-1 inhibitors. PD-1 is a checkpoint protein on immune cells that alerts them not to attack cells that express PD-L1. Some cancer cells express PD-L1, which enables them to ''switch off an immune system response. Monoclonal antibodies such as pembrolizumab and nivolumab block this signaling between PD-1 and PD-L1 and thereby reinforce the immune system response to tumor cells.

Produkteigenschaften

• Klonalität: Monoclonal
• Isotyp: IgG4
• Reinheit: Purified from cell culture supernatant by affinity chromatography

Anwendungsbeschreibung

• Application Verdünnung: ELISA 1:5000-10000, FACS 1:100