Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate, Clone: [PLCG1Y783-C4], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb PE conjugate, Clone: [PLCG1Y783-C4], Rabbit, Monoclonal
• Artikelnummer: ABI-12-4097
• Hersteller Artikelnummer: 12-4097
• Alternativnummer: ABI-12-4097-100TESTS
• Hersteller: Abeomics
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FACS
• Spezies Reaktivität: Human
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
• Konjugation: PE
• Alternative Synonym: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC1

Produktbeschreibung

The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositolphosphate to inositol triphosphate and diacylglycerol. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate diacylglycerols (DAGs) and water-soluble phosphorylated derivatives, such as inositol 1,4,5-triphosphate (IP3). Within the PLC family, PLCg is the only member that contains SH2 and SH3 domains, necessary for phospho PLCg activation. Phospho PLCg, upon activation, can interact with receptor tyrosine kinases.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [PLCG1Y783-C4]

Anwendungsbeschreibung

• Application Verdünnung: For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.