Anti-Influenza A, Nucleocapsid, Clone: [IA-3808], Mouse, Monoclonal
Artikelnummer:
ABI-12-8408
Hersteller Artikelnummer:
12-8408
Alternativnummer:
ABI-12-8408-250UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA
Alternative Synonym:
Common flu NP, Influenza A virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N, Seasonal Influenza A (H1N1) Nucleocapsid Protein
Specificity: Anti-Influenza A, Nucleoprotein (Clone IA-3808) is reactive with >50 separate isolates from H1 through H14. Background: There are four types of Influenza (flu) viruses: type A, B, C, and D. Influenza A and B viruses are routinely spread in people and other mammals, while also known for seasonal flu epidemics each year. Influenza A is the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Influenza A is classified into two main protein subtypes, hemagglutinin (HA) and neuraminidase (NA), located on the surface of the virus. Breaking down the proteins further, there are 18 hemagglutinin subtypes and 11 different neuraminidase subtypes1. Influenza A can be even further classified into specific clades (also known as groups) and sub-clades (also known as sub-groups) based on similarity of their HA/NA gene sequences1. The Nucleocapsid protein or nucleoprotein (NP) of the influenza virus A negative-strand RNA?s primary function is to encapsulate the virus genome for the purpose of RNA transcription, replication and packaging2. Specifically, NP is the most abundant viral protein in infected cells2, therefore the NP can be and has been used for anti-influenza drug development3. The NP of influenza A and B viruses share up to 38% of their amino acid sequence, indicating region functionality differences at the amino acid level4.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[IA-3808]
Reinheit:
Purity :>90% monomer by analytical SEC and SDS-PagePreparation : This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.
Target-Kategorie:
A/Texas Strain
Application Verdünnung:
ELISA Recommended starting range 1:20-1:200 IF Recommended starting range 1:10-1:50 IHC
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