Recombinant human ACE2 (Gln18-Ser740) produced by using human HEK293 cells
Alternative Synonym:
ACE-2, ACEH, ACE2
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[DM48]
Reinheit:
Purified from cell culture supernatant by affinity chromatography
