MIP-2 Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage
Artikelnummer:
ABI-14-104ACL
Hersteller Artikelnummer:
14-104ACL
Alternativnummer:
ABI-14-104ACL-1VIAL
Hersteller:
Abeomics
Kategorie:
Zellen/Zellkultur
Applikation:
FA
The MIP-2 Leeporter(TM) Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the MIP-2 promoter. Macrophage inflammatory protein 2 (MIP-2) is a small cytokine that belongs to the C-X-C chemokine family and is also known as CXCL2. MIP-2 is one of the major proinflammatory cytokines, which is induced by innate immune receptors such TLRs and Nods, and also mediates LPS-induced osteoclastogenesis. The MIP-2 induction by Toll-like receptor 4 (TLR4) ligand, LPS, is shown in Figure 1.
Application Verdünnung:
Application: Monitor the MIP-2 induction activity. Screen for activators or inhibitors of the MIP-2 signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate) supp
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