TNF-alpha Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage

Produktübersicht

• Artikelname: TNF-alpha Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage
• Artikelnummer: ABI-14-106ACL
• Hersteller Artikelnummer: 14-106ACL
• Alternativnummer: ABI-14-106ACL-1VIAL
• Hersteller: Abeomics
• Kategorie: Zellen/Zellkultur
• Applikation: FA

Produktbeschreibung

The TNF-alpha Leeporter(TM) Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimers disease. The TNF-alpha induction by lipopolysaccharide (LPS), the Toll-like receptor 4 (TLR4) ligand, is shown in Figure 1.

Anwendungsbeschreibung

• Application Verdünnung: Application: Monitor the TNF-alpha induction activity. Screen for activators or inhibitors of the TNF-alpha signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruva