TNF-beta Leeporter(TM) Luciferase Reporter-HEK293 Cell Line Preis auf Anfrage

Produktübersicht

• Artikelname: TNF-beta Leeporter(TM) Luciferase Reporter-HEK293 Cell Line Preis auf Anfrage
• Artikelnummer: ABI-14-107ACL
• Hersteller Artikelnummer: 14-107ACL
• Alternativnummer: ABI-14-107ACL-1VIAL
• Hersteller: Abeomics
• Kategorie: Zellen/Zellkultur
• Applikation: FA

Produktbeschreibung

The TNF-beta Leeporter(TM) Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-beta promoter. Tumor necrosis factor-beta (TNF-beta) one of the major proinflammatory cytokines, which is produced predominantly by mitogen-stimulated T lymphocytes and leukocytes. TNF-beta is involved in the regulation of various biological processes such as cell proliferation, differentiation and apoptosis. TNF-beta gene polymorphisms are also significantly associated with disease susceptibility and phenotype in patients with psoriatic arthritis. The TNF-beta induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.

Anwendungsbeschreibung

• Application Verdünnung: Application: Monitor the TNF-beta induction activity. Screen for activators or inhibitors of the TNF-beta signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate