ISRE Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage
Artikelnummer:
ABI-14-141ACL
Hersteller Artikelnummer:
14-141ACL
Alternativnummer:
ABI-14-141ACL-1VIAL
Hersteller:
Abeomics
Kategorie:
Zellen/Zellkultur
Applikation:
FA
The ISRE Leeporter(TM) Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Interferon-Stimulated Response Element (ISRE), so that the cell line is designed to monitor the JAK/STAT signaling pathway activity. This cell line can be activated by type I IFNs as well as certain Toll like receptor ligands capable of induction of IRFs such as TLR3 ligand-poly(I:C). Functional activity of the cell line has been validated by poly(I:C) (Figure 1).
Application Verdünnung:
Application: Monitor the JAK/STAT signaling pathway activity. Screen for activators or inhibitors of the JAK/STAT signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium
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