CCR5 Stable Cell Line is a stably transfected CHO-K1 cell line which expresses human CCR5 (C-C chemokine receptor type 5, also known as CCR5 or CD195). CCR5 belongs to the beta chemokine receptor family of integral membrane proteins, which is predominantly expressed in T cells, macrophages, dendritic cells and eosinophils. CCR5 is known to be an entry receptor together with CXCR4 for HIV-1 virus. Sequence data: Human CCR5 (accession number NP_000570) MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLT VPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLP GIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIV YFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCK CCSIFQQEAPERASSVYTRSTGEQEISVGL
Application Verdünnung:
Application:. Screen for antibodies of human CCR5 through Flow Cytometry. Culture conditions: Cells should be grown at 37oC with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate) supplemented with 10% heat-inactivated FBS and 1
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