Molecular Characterization: Mouse Trop2(Gln25-Gly270) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 54.1 kDa after removal of the signal peptide.The apparent molecular mass of mTrop2-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse Trop2 protein with C-terminal human Fc tagThis gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high Molecular weight: tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and distal arthrogryposis syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
