Molecular Characterization:6A-His tag NCL(Val2-Glu710)Molecular weight: The protein has a predicted molecular mass of 77.3 kDa after removal of the signal peptide. The apparent molecular mass of His-NCL is approximately 100-130 kDa due to glycosylation.Description: Recombinant human NCL protein with N-terminal6A-His tagNucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
