Recombinant Cynomolgus ANXA2 Protein, His Tag, Human
Artikelnummer:
ABI-32-17836-100
Hersteller Artikelnummer:
32-17836-100
Alternativnummer:
ABI-32-17836-100-100UG
Hersteller:
Abeomics
Wirt:
Human
Kategorie:
Proteine/Peptide
Alternative Synonym:
Annexin
Molecular Characterization: ANXA2(Ser2-Asp339)6A-His tagMolecular weight: The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide. The apparent molecular mass of cANXA2-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant Cynomolgus ANXA2 protein with C-terminal6A-His tagThis gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
