Molecular Characterization: CD235A(His28-Glu91) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 33.3 kDa after removal of the signal peptide. The apparent molecular mass of CD235A-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant human CD235A protein with C-terminal human Fc tagGlycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
