Molecular Characterization: TMIGD2(Leu23-Gly150) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of TMIGD2-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant human TMIGD2 protein with C-terminal human Fc tagPlays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.[UniProtKB/Swiss-Prot Function]
