Leucine-rich repeats and immunoglobulin-like domains protein 1?LIG-1
Molecular Characterization: LRIG1(Ala35-Thr792)6A-His tagMolecular weight: The protein has a predicted molecular mass of 84 kDa after removal of the signal peptide. The apparent molecular mass of LRIG1-His is approximately 100-130 kDa due to glycosylation.Description: Recombinant human LRIG1 protein with C-terminal6A-His tagActs as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.[UniProtKB/Swiss-Prot Function]