Recombinant Human ACE-2 (C-Fc) Active

Produktübersicht

• Artikelname: Recombinant Human ACE-2 (C-Fc) Active
• Artikelnummer: ABI-32-190007-10
• Hersteller Artikelnummer: 32-190007-10
• Alternativnummer: ABI-32-190007-10-10UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

Produktbeschreibung

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor dona€(TM)t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

Produkteigenschaften

• UniProt: Q9BYF1
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE.
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Immobilized Human ACE-2-FC at 10µg/ml (100 µl/well) can bind 2019-nCoV S Protein RBD-SD1-mFc. The ED50 of Recombinant 2019-nCoV S Protein RBD-mFc is 15.5 ng/ml .